Post by kickingfrog on Jan 28, 2012 10:26:10 GMT
Celiac Disease and Chronic Obstructive Pulmonary Disease (COPD)
Celiacs at Higher Risk for COPD Before, After Diagnosis
By Jane Anderson, About.com Guide
Updated September 26, 2011
....Study Shows Increased COPD Risk for Celiacs
There are few medical studies on COPD risk in celiac disease, but the available research indicates there is an increased risk.
A team of researchers in Sweden used that country's excellent national health database to identify all people with biopsy-proven celiac disease who had been diagnosed between 1987 and 2008. They found 10,990 individuals and matched them with 54,129 control subjects without celiac. They then looked to see how many had been diagnosed with COPD.
A total of 3.5% of individuals with celiac disease also had been diagnosed with COPD, compared with 2.6% of the control subjects, indicating about a 25% increase in risk for COPD if you have celiac disease.
The risk dropped somewhat after people were diagnosed with celiac disease, but still remained higher than normal in the five years following their celiac disease diagnoses.
Heightened Risk Could Relate to Inflammation, Nutritional Status
It's not clear why people with celiac disease might have an increased risk for COPD.
The authors of the Swedish study noted that chronic inflammation plus poor nutritional status can influence the development of chronic obstructive pulmonary disease. Since celiac disease "is characterized both by dysregulated inflammation and malnutrition," they said, they decided to investigate if there was an association.
Other researchers, citing case reports, also have noted a possible association between the two conditions.
Does celiac disease cause COPD? No, most people develop COPD because they smoked or were exposed to secondhand smoke. However, having celiac disease,whether it's diagnosed or not, might increase your chances of developing COPD as you get older, especially if you have other risk factors for the lung illness.
Sources:
De Menthon M. et al. Undiagnosed coeliac disease in patients with emphysema: a fortuitous association? European Respiratory Journal. 2010 Aug 1. 36(2):453-6.
Ludvigsson J.F. et al. A nationwide cohort study of the risk of chronic obstructive pulmonary disease in coeliac disease. Journal of Internal Medicine. 2011 Aug 31. doi: 10.1111/j.1365-2796.2011.02448.x (Epub ahead of print)
celiacdisease.about.com/od/commoncomplicationsofcd/a/Celiac-Disease-Copd.htm
Celiacs at Higher Risk for COPD Before, After Diagnosis
By Jane Anderson, About.com Guide
Updated September 26, 2011
....Study Shows Increased COPD Risk for Celiacs
There are few medical studies on COPD risk in celiac disease, but the available research indicates there is an increased risk.
A team of researchers in Sweden used that country's excellent national health database to identify all people with biopsy-proven celiac disease who had been diagnosed between 1987 and 2008. They found 10,990 individuals and matched them with 54,129 control subjects without celiac. They then looked to see how many had been diagnosed with COPD.
A total of 3.5% of individuals with celiac disease also had been diagnosed with COPD, compared with 2.6% of the control subjects, indicating about a 25% increase in risk for COPD if you have celiac disease.
The risk dropped somewhat after people were diagnosed with celiac disease, but still remained higher than normal in the five years following their celiac disease diagnoses.
Heightened Risk Could Relate to Inflammation, Nutritional Status
It's not clear why people with celiac disease might have an increased risk for COPD.
The authors of the Swedish study noted that chronic inflammation plus poor nutritional status can influence the development of chronic obstructive pulmonary disease. Since celiac disease "is characterized both by dysregulated inflammation and malnutrition," they said, they decided to investigate if there was an association.
Other researchers, citing case reports, also have noted a possible association between the two conditions.
Does celiac disease cause COPD? No, most people develop COPD because they smoked or were exposed to secondhand smoke. However, having celiac disease,whether it's diagnosed or not, might increase your chances of developing COPD as you get older, especially if you have other risk factors for the lung illness.
Sources:
De Menthon M. et al. Undiagnosed coeliac disease in patients with emphysema: a fortuitous association? European Respiratory Journal. 2010 Aug 1. 36(2):453-6.
Ludvigsson J.F. et al. A nationwide cohort study of the risk of chronic obstructive pulmonary disease in coeliac disease. Journal of Internal Medicine. 2011 Aug 31. doi: 10.1111/j.1365-2796.2011.02448.x (Epub ahead of print)
celiacdisease.about.com/od/commoncomplicationsofcd/a/Celiac-Disease-Copd.htm