Post by kickingfrog on Feb 3, 2011 12:58:34 GMT
Marsh: grades of damage to gut
From CUK
…Previously CD was diagnosed only in those with total or sub-total villous atrophy, but now there are several grades of gut damaged that are recognised. These have been classified by Marsh, and include the infiltration of lymphocytes without villous atrophy and crypt hyperplasia, as well as various stages of villous atrophy ….
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…Marsh MN . Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue'). Gastroenterology 1992;102:330-54.
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From CUK
…Previously CD was diagnosed only in those with total or sub-total villous atrophy, but now there are several grades of gut damaged that are recognised. These have been classified by Marsh, and include the infiltration of lymphocytes without villous atrophy and crypt hyperplasia, as well as various stages of villous atrophy ….
*******
…Marsh MN . Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue'). Gastroenterology 1992;102:330-54.
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